Magnetic Iron Oxide Nanocrystals in a Solvent MSDS

1. PRODUCT IDENTIFICATION
CAS No.: 1317-61-9
Inorganic Unit (Fe₃O₄): 231.535
Chemical Name: Iron Oxide Nanocrystals
Chemical Formula: Fe₃O₄ [Iron (II,III) oxide]
Chemical Family: Metal Oxides
Typical Solvents (CAS No): Toluene (108-88-3), Hexanes (110-54-3), Chloroform (67-66-3),
Dichloromethane (75-09-2), Water

2. COMPOSITION/INFORMATION ON INGREDIENT (EACH VIAL)

Substance Name	CAS #	Percentage of Whole (by weight)
Iron Oxide	1317-61-9	3.0%
Oleic Acid	112-80-1	2.0%
Toluene	108-88-3	95%

3. HAZARDS IDENTIFICATION
Iritating to eyes, respiratory system, and skin.
HMIS ratings (scale 0-4) (Iron Oxide only, does not include solvent)
         Health = 1
         Flammability = 0
         Reactivity = 0

4. FIRST AID MEASURES
Inhalation: Supply fresh air. If required, provide artificial respiration. Keep patient warm. Seek immediate
medical advice.
Skin contact: Immediately wash with water and soap and rinse thoroughly. Seek immediate medical advice.
Eye contact: Rinse opened eye for several minutes under running water. Then consult a doctor.
Ingestion: Seek immediate medical advice.

5. FIRE FIGHTING MEASURES
Suitable extinguishing agents: Product is not flammable but the solvent is. Use fire fighting measures that
suit the necessary solvent type.
Protective equipment: Wear self-contained respirator if necessary. Wear protective gloves.

6. ACCIDENTAL RELEASE MEASURES
Person-related safety precautions: Wear protective equipment. Keep unprotected persons away. Ensure
adequate ventilation
Measures for environmental protection: Do not allow material to be released to the
environment without proper governmental permits.
Measures for cleaning/collecting: Dispose contaminated material as waste according to item 12. Ensure
adequate ventilation.

7. HANDLING AND STORAGE
Information for safe handling: Keep container tightly sealed. Store at room temperature in a tightly sealed
container. Ensure good ventilation at the workplace. Store dissolved in solvent to prevent the formation of
dust.
Information about protection against explosions and fires: Know the requirements of the necessary
solvent.
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Do not store together with acids.
Further information about storage conditions: Keep container tightly sealed. Store at room
temperature in a tightly sealed container. Ensure good ventilation at the workplace. Store dissolved
in solvent to prevent the formation of dust.

8. EXPOSURE CONTROLS AND PERSONAL PROTECTION
Additional information about design of technical systems: Properly operating chemical fume hood
designed for hazardous chemicals and having an average face velocity of at least 100 feet per minute.
General protective and hygienic measures: The usual precautionary measures for handling chemicals
should be followed. Keep away from foodstuffs, beverages, and feed. Remove all soiled and contaminated
clothing immediately. Wash hands before breaks and at the end of work. Avoid contact with the eyes and
skin.
Breathing equipment: Use suitable respirator when high concentrations are present.
Protection of hands: Impervious gloves
Eye protection: Safety glasses
Body protection: Protective work clothing.

9. PHYSICAL AND CHEMICAL PROPERTIES:
Form: Liquid form. Crystalline powder, dissolved in a solvent
Color: Black
Odor: Odor dependent upon solvent used. Crystalline powder is odorless
Melting point/Melting range: ~1538℃ to bulk melting point of Fe₃O₄ crystals. The solvent is liquid and
depends on the chemical composition of the solvent.
Boiling point/Boiling range: Determined by solvent used
Sublimation temperature / start: Not determined
Flash point: Dependent upon solvent used
Ignition temperature: Dependent upon solvent used
Decomposition temperature: Not determine
Danger of explosion: Dependent upon solvent used. Crystalline powder does not present an explosion hazard.
Explosion limits: Currently unknown for nanocrystals
Vapor pressure: Dependent upon solvent used
Density: 5.2 g/cm3 (crystal at 20℃) for the nanocrystal powder if isolated
Solubility in / Miscibility with Polar Solvents: Soluble when hydrophilic ligands are present
Solubility in / Miscibility with Non-Polar Solvents: Soluble when hydrophobic ligands are present

10. STABILITY AND REACTIVITY
Thermal decomposition / conditions to be avoided: Not determined, but temperature increases will effect
the solvent used. Be aware of the necessary warnings for the specific solvent used.
Materials to be avoided: Acids, Bases, Oxidants, Reductants, and Ligands to the nanocrystals should be
used with caution.
Dangerous reactions: No dangerous reactions known for nanaocrystals but look up specifics for the solvent

11. TOXICOLOGICAL INFORMATION (For Iron Oxide Only)
Skin: Irritant to skin and mucous membranes.
Eye: Irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information: Danger through skin absorption is unknown.
To the best of our knowledge the acute and chronic toxicity of this substance is not fully known. However,
preliminary studies suggest Iron Oxide nanocrystals are not toxic.
Target Organs: Possiblly Liver and Kidney
EPA-B1: Not Carcinogenic
IARC-1: Not Carcinogenic
NTP-2: Not Carcinogenic
ACGIH A2: Not Carcinogenic
WARNING: Many of the toxic effects of Iron Oxide nanocrystals are still being researched and are currently
unknown at this point. Use at own risk.

12. ECOLOGICAL INFORMATION:
Do not allow material to be released to the environment without proper governmental permits.

13. DISPOSAL CONSIDERATIONS
Consult local or national regulations for proper disposal.

14. TRANSPORT INFORMATION (Solvent Specific)-When dissolved in Toluene
(Iron Oxide is not a hazardous material for transportation)
U.S. DOT 49 CFR 172.101 ID Number: UN1294
Hazard class: 3
Packing Group: II
Labeling Requirements: Flammable Liquid (Unnecessary when Water is the solvent)
Canadian Transportation of Dangerous Goods: UN1294, Class 3
Land Transport ADR/RID: UN1294, Class 3, Class Code F1, Pack group II
Air Transport IATA/ICAO: UN1294, Class or Division 3, Pack group II
Exceptions: 49 CFR 173.4

15. REGULATIONS
Hazard symbols: Xi Irritant
Risk phrases: 36/37/38 Irritating to eyes, respiratory system and skin
Safety phrases: (22) Do not breathe dust or vapors. (26) In case of contact with eyes, rinse immediately with
plenty of water and seek medical advice. (37/39) Wear suitable gloves and eye/face protection.
National regulations: All components of this product are listed in the U.S. Environmental Protection Agency
Toxic Substances Control Act Chemical Substance Inventory.
Information about limitation of use: For use only by technically qualified individuals.